Main pathways for treatment of keratinocyte cancer. BCC/SCC have not been separated nor categorised by invasive, superficial, etc., because treatment is largely the same. Excision is the mainstay treatment modality. Radiotherapy is required if perineural invasion has occurred, performed in hospital, or for field treatment of multiple SCCs in the same area, e.g., forehead. Mohs surgery can be performed for an improved cosmetic outcome in a difficult facial area. Topical creams include imiquimod and 5-FU fluorouracil. GPs and skin cancer GPs perform much of the excisional treatments, whereas dermatologists and plastic surgeons treat more complex cases. A small proportion are referred to hospital dermatology departments where organ transplant recipients (as a very high-risk group) are also treated for skin cancers.