Table 4.

Multivariable Cox hazards analysis of colorectal cancer patients.

	Hazard	95% CI
	Ratio	Min	Max	p-Value
Well to moderately differentiated histology	0.17	0.09	0.33	<0.0001
Age (<70)	0.52	0.30	0.91	0.021
Sex (female)	0.55	0.31	0.99	0.046
p53 complete loss	2.16	1.21	3.86	0.0087
Incomplete resection	2.65	1.31	5.35	0.0068
Peritoneal metastasis	5.32	2.97	9.54	<0.0001

The multivariable Cox hazards analysis model initially included sex, age, primary tumor location, tumor size, pT stage, surgical status, tumor histology, mucus production, lymph node metastasis, distant organ metastasis, peritoneal metastasis, mismatch repair system status, and immunoreactivity for p53 (Complete loss vs. others). A backward elimination with a threshold of p = 0.05 was used to select variables in the final model.