Table 2.
Functional outcomes in patients randomized to the intervention group who completed the study (N = 26) *.
| Inclusion | Close-Out | Change | |
|---|---|---|---|
| EDSS | 4.2 (2.1) [0] | 4.2 (2.3) [0] | 0.1 (0.9) [0]; 0.82 |
| T25FWT | 15.6 (34.4) [0] | 26.6 (53.1) [1] | 10.8 (34.1) [1]; 0.75 |
| 9HPT-dom | 25.6 (13.7) [0] | 24.7 (9.9) [1] | −0.8 (11.8) [1]; 0.82 |
| 9HPT-ndom | 34.4 (53.5) [0] | 37.4 (55.0) [1] | 2.4 (11.9) [1]; 0.77 |
| SDMT | 58.3 (12.5) [2] | 55.0 (13.6) [2] | −1.8 (10.0) [4]; 0.38 |
| FSS | 4.9 (1.2) [0] | 4.6 (1.7) [0] | −0.3 (1.2) [0]; 0.03 |
| BDI | 10.9 (7.2) [0] | 11.5 (11.4) [0] | 0.7 (6.9) [0]; 0.56 |
| HADS-anx | 6.7 (4.0) [0] | 6.3 (4.9) [0] | −0.3 (5.3) [0]; 0.55 |
| HADS-dep | 5.0 (3.5) [0] | 5.5 (5.2) [0] | 0.5 (4.6) [0]; 0.58 |
| PSQI | 6.3 (3.7) [1] | 6.8 (4.7) [5] | −0.2 (4.0) [5]; 0.69 |
| MSIS-29-phy | 29.1 (20.2) [1] | 34.6 (24.8) [0] | 4.8 (18.1) [1]; 0.33 |
| MSIS-29-psy | 29.2 (22.5) [3] | 29.2 (24.2) [0] | 1.3 (23.9) [3]; 0.79 |
EDSS: Expanded Disability Status Scale; T25FWT: Timed 25-Foot Walk Test; 9HPT-dom: Nine-Hole Peg Test for dominant hand; 9HPT-ndom: Nine-Hole Peg Test for non-dominant hand; SDMT: Symbol Digit Modalities Test; FSS: Fatigue Severity Scale; BDI: Beck Depression Inventory; HADS-anx: Hospital Anxiety and Depression Scale for anxiety; HADS-dep: Hospital Anxiety and Depression Scale for depression; PSQI: Pittsburgh Sleep Quality Index (PSQI); MSIS-29-psy: Multiple Sclerosis Impact Scale for psychological impact; MSIS-29-phy: Multiple Sclerosis Impact Scale for physical impact. * Scores expressed as mean (SD) [missing values]; p value for comparison with the respective change in the control group, as expressed in Table 3.