Table 1.
Assessment of cognitive function in the different treated groups by the Morris water maze (MWM) test (mean ± SD).
| Groups Latency to Reach Target Quadrant (s) | Day 1 | Day 2 | Day 3 | Day 4 | Day 5 | Day 6 | % Time Spent in Target Quadrant |
|---|---|---|---|---|---|---|---|
| Control group | 6.68 ± 19.9 | 27.88 ± 6.6 | 22.18 ± 8.1 | 15.3 ± 7.5 | 8.37 ± 2.5 | 7.7 ± 4.9 | 47.33 ± 7.5 |
| Alcohol group | 10.9 ± 9.9 a | 67.63 ± 5.4 a | 92.9 ± 7.1 a | 55.52 ± 6.3 a | 45.38 ± 8.2 a | 21.08 ± 7.2 a | 19.25 ± 5.9 a |
| ATOR group | 8.06 ± 17.2 a | 50.77 ± 10.2 a | 80.9 ± 9.8 a | 32.6 ± 5.8 a | 35.33 ± 13.3 a | 19.17 ± 6.4 a | 21.6 ± 10.3 a |
| Alcohol + ATOR group | 13.71 ± 7.3 a | 85.19 ± 8.8 a | 71.46 ± 7.7 a | 48.23 ± 13.2 a | 55.5 ± 11.9 a | 33.17 ± 9.2 a | 12.81 ± 14.9 a |
| Alcohol + ATOR + ASA group | 7.73 ± 16.6 abcd | 33.1 ± 15.1 abcd | 32.23 ± 7.1 abcd | 21.17 ± 11.4 abcd | 21.9 ± 11.0 abcd | 15.08 ± 5.2 abcd | 36.6 ± 18.2 bcd |
Data are mean ± SD of 6 rats per group. p < 0.05 is significant; a P versus control group, b P versus Alcohol group, c P versus ATOR group, d p versus Alcohol + ATOR + ASA group.