Table 4.
Organism | Genotype | Terbinafine MIC (μg/mL) | Nucleotide Substitution (SQLE) |
Amino Acid Substitution (SQLE) |
Accession Number |
---|---|---|---|---|---|
T. indotineae | 0.03 | Wt | Wt | OL415218 | |
0.03 | G1342A | Ala448Thr | OL415219 | ||
0.015 | Wt | Wt | OL415223 | ||
0.015 | G1342A | Ala448Thr | OL415220 | ||
0.008 | G1342A | Ala448Thr | OL415222 | ||
2 | T1178C | Leu393Ser | OL415221 | ||
T. rubrum | ND | Wt | Wt | OL415199 | |
ND | Wt | Wt | OL415200 | ||
4 | C1191A | Phe397Leu | OL415198 | ||
T. interdigitale | I | 0.008 | Wt | Wt | OL415202 |
0.008 | Wt | Wt | OL415203 | ||
0.008 | Wt | Wt | OL415206 | ||
0.015 | Wt | Wt | OL415207 | ||
0.008 | Wt | Wt | OL415211 | ||
8 | C1191A | Phe397Leu | OL415213 | ||
II | 0.008 | Wt | Wt | OL415208 | |
0.008 | Wt | Wt | OK632159 | ||
0.008 | Wt | Wt | OL415212 | ||
0.008 | Wt | Wt | OL415210 | ||
T. mentagrophytes | II* | 0.03 | Wt | Wt | OL415214 |
III* | 0.03 | C1255T | Leu419Phe | OL415215 | |
0.03 | C1255T | Leu419Phe | OL415216 | ||
G828C | Lys276Asn | ||||
VII | 0.03 | C1255T | Leu419Phe | OL415217 | |
G828C | Lys276Asn |
ND = EUCAST was not performed for these isolates but both isolates did not grow in the terbinafine containing agar plates.