Skip to main content
. 2022 Feb 23;8(3):220. doi: 10.3390/jof8030220

Table 4.

Squalene epoxidase enzyme sequencing of 3 TerR and 20 susceptible isolates collected in the Paris area, France.

Organism Genotype Terbinafine MIC (μg/mL) Nucleotide
Substitution (SQLE)
Amino Acid
Substitution (SQLE)
Accession Number
T. indotineae 0.03 Wt Wt OL415218
0.03 G1342A Ala448Thr OL415219
0.015 Wt Wt OL415223
0.015 G1342A Ala448Thr OL415220
0.008 G1342A Ala448Thr OL415222
2 T1178C Leu393Ser OL415221
T. rubrum ND Wt Wt OL415199
ND Wt Wt OL415200
4 C1191A Phe397Leu OL415198
T. interdigitale I 0.008 Wt Wt OL415202
0.008 Wt Wt OL415203
0.008 Wt Wt OL415206
0.015 Wt Wt OL415207
0.008 Wt Wt OL415211
8 C1191A Phe397Leu OL415213
II 0.008 Wt Wt OL415208
0.008 Wt Wt OK632159
0.008 Wt Wt OL415212
0.008 Wt Wt OL415210
T. mentagrophytes II* 0.03 Wt Wt OL415214
III* 0.03 C1255T Leu419Phe OL415215
0.03 C1255T Leu419Phe OL415216
G828C Lys276Asn
VII 0.03 C1255T Leu419Phe OL415217
G828C Lys276Asn

ND = EUCAST was not performed for these isolates but both isolates did not grow in the terbinafine containing agar plates.