Table 1.
Characteristics of 562 subjects with malignant pleural mesothelioma (MPM) and interview selected for the PRIMATE study, Lombardy, Italy, 2000–2019.
| Men | Women | |||
|---|---|---|---|---|
| N | % | N | % | |
| Total | 372 | 100 | 190 | 100 |
| Age at diagnosis (years) mean (min-max) | 68.8 | (24.5–94.5) | 69.3 | (41.3–93.1) |
| Period of diagnosis | ||||
| 2000–2009 | 111 | 29.8 | 64 | 33.7 |
| 2010–2019 | 261 | 70.2 | 126 | 66.3 |
| Diagnosis | ||||
| Definite | 367 | 98.7 | 187 | 98.4 |
| Probable | 5 | 1.3 | 3 | 1.6 |
| Morphology (ICD-O code) # | ||||
| MM not otherwise specified (90503) | 6 | 1.6 | 5 | 2.6 |
| Fibrous/sarcomatoid/desmoplastic MM (90513) | 20 | 5.4 | 15 | 7.9 |
| Epithelioid MM (90523) | 262 | 70.4 | 148 | 77.9 |
| Biphasic MM (90533) | 84 | 22.1 | 22 | 11.6 |
| Presence of pleural plaques | 65 | 17.5 | 28 | 14.7 |
| Presence of asbestosis | 8 | 2.1 | 0 | 0.0 |
| Interview | ||||
| Patient | 279 | 75.0 | 131 | 69.0 |
| Relative | 93 | 25.0 | 59 | 31.0 |
| Vital status | ||||
| Dead | 352 | 94.6 | 177 | 92.7 |
| Alive | 20 | 5.4 | 13 | 6.8 |
| Asbestos exposure (ReNaM) | ||||
| Occupational, definite | 247 | 66.4 | 35 | 18.4 |
| Occupational, probable | 3 | 0.8 | 2 | 1.0 |
| Occupational, possible | 24 | 6.4 | 8 | 4.2 |
| Para-occupational | 7 | 1.9 | 18 | 9.5 |
| Home-related | 2 | 0.5 | 10 | 5.3 |
| Environmental | 20 | 5.4 | 42 | 22.1 |
| None identified | 69 | 18.5 | 75 | 39.5 |
|
Years since first asbestos exposure (RML) mean (min–max) |
48.8 | (18.5–78.1) | 52.5 | (16.6–85.1) |
|
Years since first occupational asbestos exposure (RML) mean (min–max) |
48.1 | (18.5–71.5) | 53.3 | (17.8–69.6) |
|
Duration of occupational asbestos exposure (RML) mean (min–max) |
23.6 | (0.5–60.4) | 16.1 | (1.0–43.0) |
| Occupational asbestos exposure: industry * (RML) | ||||
| Metalworking and metallurgy | 92 | 33.6 | 5 | 11.1 |
| Construction | 73 | 26.6 | 0 | 0.0 |
| Asbestos-cement | 32 | 11.7 | 2 | 4.4 |
| Textile and clothing production | 8 | 2.9 | 22 | 48.9 |
| Motor vehicle production | 20 | 7.3 | 0 | 0.0 |
| Transport | 16 | 5.8 | 0 | 0.0 |
| Chemical | 15 | 5.5 | 0 | 0.0 |
| Railroad production and maintenance | 15 | 5.5 | 0 | 0.0 |
| Food and beverage | 11 | 4.0 | 2 | 4.4 |
| Health and social services | 4 | 1.5 | 8 | 17.8 |
| Military | 10 | 3.6 | 0 | 0.0 |
| Occupational asbestos exposure (SYN-JEM) | ||||
| Ever | 225 | 60.5 | 25 | 13.2 |
| Cumulative (f/mL-years) median (min–max) | 1.7 | (0.01–11.9) | 1.2 | (0.1–3.1) |
| Duration (years) median (min–max) | 24.5 | (1–61) | 11.4 | (2.0–28.0) |
# ICD-O, International Classification of Diseases for Oncology, Third Edition; MM, malignant mesothelioma. * Only industries with at least 10 exposed cases are listed; a subject may have been exposed to asbestos in more than one industrial sector in his/her occupational history.