RCC	Renal cell carcinoma
ccRCC	clear cell renal cell carcinoma
miRNA	microRNA
TAMs	Tumor-associated macrophages
THP-1-Mφ	Mφ subtype differentiated from THP-1 cell
THP-1-M2	M2 subtype differentiated from THP-1 cell
M2-Exos	Exosomes derived from M2 macrophages
miR-21-Inh	miR-21-5p inhibitor
miR-21-NC	miR-21-5p negative control
miR-21-Inh-Exos	Exosomes derived from M2 macrophages transfected with miR-21-Inh
miR-21-NC-Exos	Exosomes derived from M2 macrophages transfected with miR-21-NC
CAM	Chorioallantoic membrane
DLS	Dynamic light scattering
DAPI	4′,6-diamidino-2-phenylindole
GAPDH	Glyceraldehyde-3-phosphate dehydrogenase
H&E	Hematoxylin and Eosin
IHC	Immunohistochemistry
IF	Immunofluorescence
3′UTRs	the 3′-untranslated regions of mRNA
qPCR	quantitative PCR
RT-qPCR	Reverse transcription-qPCR
PTEN	Phosphatase and tensin homolog
CD163	Cluster of differentiation 163
CD206	Cluster of differentiation 206
HLA-DR	Human leukocyte antigen-DR isotype
TNF-α	Tumor necrosis factor alpha
MMP-9	Matrix metalloproteinase 9
EMT	Epithelial-mesenchymal transition