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(a) ALP activity after 7 days, and mineralization after (b) 14 and (c) 21 in microtissues assembled from siRNA-loaded cGM and hMSC cultured in osteogenic medium with or without BMP-2 (ctr: non-treated control, nc: non-coding siRNA, chrd: chordin siRNA). Statistically significant differences (p < 0.05) are indicated with (*).
