Two groups similar and recruited from the same population |
Yes |
Yes |
Yes |
Yes |
Yes |
Exposures measured similarly to assign people to both exposed and unexposed groups |
Yes |
Yes |
Yes |
Yes |
Yes |
Exposure measured in a valid and reliable way |
Yes |
Yes |
Yes |
Yes |
Yes |
Objective criteria for measurement of the condition |
Yes |
Yes |
Yes |
Yes |
Yes |
Confounding factors identified |
Yes |
Yes |
Yes |
Yes |
Yes |
Strategies for dealing with confounders |
Unclear |
Yes |
Yes |
Yes |
Yes |
Participants free of the outcome at the start of the study |
Yes |
Yes |
No |
Unclear |
Unclear |
Outcomes measured in a valid and reliable way |
Yes |
Yes |
Yes |
Yes |
Yes |
The follow up time reported and sufficient to be long enough for outcomes to occur |
Yes |
Yes |
Yes |
Yes |
Yes |
Complete follow-up or presentation of the reasons for the loss of follow-up |
Yes |
Yes |
Yes |
Unclear |
Unclear |
Strategies to address incomplete follow up utilized |
Yes |
Yes |
Yes |
Unclear |
Unclear |
Appropriate statistical analysis |
Yes |
Yes |
Yes |
Yes |
Yes |