Figure 5.

(a) In vitro photothermal images of CA800Cl solution (100 μM in PBS) and PBS alone (100 μL) exposed to an 808 nm laser (1.1 W/cm²) for 1 min. The maximum temperature was automatically recorded using an infrared thermal camera as a function of irradiation time. (b) Temperature changes in the solutions in each sample were monitored during the 1 min of laser irradiation. (c) Photothermal stability curve of 100 μM CA800Cl solutions after repeated laser irradiation (1 cycle = 1 min of laser irradiation). (d) Whole-body photothermal images of tumor-bearing mice 24 h post-injection of PBS or CA800Cl upon exposure to 808 nm laser irradiation (1.1 W/cm²) for 5 min. (e) Temperature changes at the tumor sites in each treatment group were monitored during the 5 min of 808 nm laser irradiation. Data are expressed as mean ± S.D. (n = 3).