Figure 6.

In vivo phototherapeutic efficacy of CA800Cl NIR fluorophore. (a) Representative photos of changes in tumor size in NCI-H460 tumor-bearing mice for 9 days after different treatments. The laser groups were treated with 24 h post-injections of PBS, IR-786, CA800H, and CA800Cl, followed by 808 nm laser irradiation (1.1 W/cm²) for 5 min. Scale bars = 1 cm. (b) Tumor growth rates and (c) body weights of each treatment group were monitored for 9 days. Data are expressed as mean ± S.D. (n = 3). ** p < 0.01. (d) Tumor sections stained with H&E from each group 24 h after different treatments. Scale bars = 100 μm.