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FOXO3 deficiency in macrophages links to mouse colonic inflammation and dysplasia. (A,B) Top canonical pathways and upstream regulators affected by FOXO3-deficient macrophages which are altered in mouse inflamed colonic tissue (n = 3, GSE31106, p < 0.05, IPA). (C,D) Top canonical pathways and upstream regulators affected by FOXO3-deficient macrophages which are altered in mouse dysplastic colonic tissue (n = 3, GSE31106, p < 0.05, IPA).
