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Effect of hemodilution on thromboelastography parameters in the presence of tPA. Thromboelastography was performed on whole blood or blood diluted by 40% (HD) + 0.4 nM tPA ± 1 or 2 mg/mL, RiaSTAP® cryoprecipitate or FibCLOT® using EXTEM reagent. (A) Representative thromboelastography traces, (B) clot formation time (CFT), (C) maximum clot firmness (MCF), (D) clot elasticity and (E) lysis onset time. * p < 0.05, ** p < 0.01, *** p < 0.001, vs. HD. n = 3.
