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. 1999 Oct;43(10):2430–2436. doi: 10.1128/aac.43.10.2430

TABLE 2.

Susceptibility levels of PSE-1 and TEM-1 Salmonella isolates to β-lactam antibioticsa

Antibiotic MIC (μg/ml)
No. resistantb
Range 50% 90%
PSE-1 producers (n = 40)
 Amoxicillin ≥2,048 >2,048 >2,048 40
 Amoxicillin-clavulanic acidc 16–32 16 16 4
 Piperacillin 256–>2,048 256 256 40
 Piperacillin-tazobactamd 4–8 4 4 0
 Cefuroxime 4–8 8 8 0
 Cefoperazone 16–512 32 32 1
 Cefotaxime 0.06–0.125 0.06 0.06 0
TEM-1 producers (n = 54)
 Amoxicillin 1,024–>2,048 2,048 >2,048 54
 Amoxicillin-clavulanic acid 8–32 16 16 1
 Piperacillin 16–>2,048 128 256 32
 Piperacillin-tazobactam 1–8 4 4 0
 Cefuroxime 2–32 4 8 1
 Cefoperazone 1–512 4 16 1
 Cefotaxime 0.03–0.5 0.06 0.125 0
a

The MICs for 2 of 96 strains (the PSE-1/TEM-2- and the OXA-4-producing strains) are not included in this table. 

b

According to the National Committee for Clinical Laboratory Standards breakpoints. 

c

Amoxicillin and clavulanic acid were associated in the ratio of 1/0.5. MIC values refer to the concentrations of amoxicillin. 

d

MIC values refer to the concentrations of piperacillin in the presence of a fixed amount of tazobactam (4 μg/ml).