Table 4.
HR (95% CIs) for distal radius fx in the PA groups with subgroup analyses according to age and gender.
| Characteristics | No. of Distal Radius fx/ No. of Participants |
Follow-Up Duration, PY |
Incidence Rate, per 100 PY |
Hazard Ratios for Distal Radius fx |
p for Interaction |
|||
|---|---|---|---|---|---|---|---|---|
| Crude 1 | p-Value | Adjusted 1,2 | p-Value | |||||
| Total participants (n = 175,860) | ||||||||
| Low PA | 8119/58,620 (13.9) | 119,633 | 6.8 | 1 | 1 | |||
| Moderate PA | 4229/58,620 (7.2) | 132,804 | 3.2 | 0.48 (0.46–0.50) | <0.001 * | 0.46 (0.45–0.48) | <0.001 * | |
| High PA | 2991/58,620 (5.1) | 137,923 | 2.2 | 0.33 (0.32–0.34) | <0.001 * | 0.32 (0.30–0.33) | <0.001 * | |
| Age group | <0.001 * | |||||||
| Age < 65 years old (n = 38,367) | ||||||||
| Low PA | 2812/12,789 (22.0) | 23,162 | 12.1 | 1 | 1 | |||
| Moderate PA | 1332/12,789 (10.4) | 28,389 | 4.7 | 0.42 (0.40–0.44) | <0.001 * | 0.41 (0.39–0.43) | <0.001 * | |
| High PA | 898/12,789 (7.0) | 30,308 | 3.0 | 0.27 (0.26–0.29) | <0.001 * | 0.26 (0.25–0.28) | <0.001 * | |
| Age ≥ 65 years old (n = 137,493) | ||||||||
| Low PA | 5307/45,831 (11.6) | 96,471 | 5.5 | 1 | 1 | |||
| Moderate PA | 2897/45,831 (6.3) | 104,415 | 2.8 | 0.57 (0.54–0.60) | <0.001 * | 0.55 (0.52–0.58) | <0.001 * | |
| High PA | 2093/45,831 (4.6) | 107,615 | 1.9 | 0.42 (0.39–0.45) | <0.001 * | 0.40 (0.38–0.43) | <0.001 * | |
| Gender | 0.008 * | |||||||
| Men (n = 21,138) | ||||||||
| Low PA | 403/7046 (5.7) | 16,895 | 2.4 | 1 | 1 | |||
| Moderate PA | 282/7046 (4.0) | 17,269 | 1.6 | 0.69 (0.59–0.81) | <0.001 * | 0.66 (0.57–0.77) | <0.001 * | |
| High PA | 212/7046 (3.0) | 17,539 | 1.2 | 0.52 (0.44–0.61) | <0.001 * | 0.49 (0.41–0.58) | <0.001 * | |
| Women (n = 154,722) | ||||||||
| Low PA | 7716/51,574 (15.0) | 102,738 | 7.5 | 1 | 1 | |||
| Moderate PA | 3947/51,574 (7.7) | 115,535 | 3.4 | 0.47 (0.45–0.49) | <0.001 * | 0.45 (0.44–0.47) | <0.001 * | |
| High PA | 2779/51,574 (5.4) | 120,384 | 2.3 | 0.32 (0.31–0.33) | <0.001 * | 0.31 (0.29–0.32) | <0.001 * | |
CCI, Charlson comorbidity index; CIs, confidence intervals; DBP, diastolic blood pressure; fx, fracture; HR, hazard ratio; PA, physical activity; PY, person–year; SBP, systolic blood pressure. * Stratified Cox proportional hazard model, significance at <0.05 with Bonferroni correction (α = 0.05/3). 1 Stratified by gender, age, income within household unit, and region of residence. 2 Adjusted for total cholesterol, SBP, DBP, fasting blood glucose, obesity, smoking, alcohol consumption, and CCI score.