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Conserved and accessible amino acids of CoV Protease. Identified conserved residues of interest within coronavirus Nsp5 protease crystal structure (PDB ID: 5GWY) shown as a monomer (A) and a dimer (B). Two conserved and accessible residues, G23 and W218, are highlighted with molecular surface representation and colored by amino acid accessible surface area (ASA) ranging from the least accessible (dark blue) to the most accessible (red).
