Figure 3.
Immature lattice establishment and assembly progression. Side view (A) and top view (B) of lattice formation and growth. Initial Gag complexes arrive at the plasma membrane from the cytosol, potentially in complex with genomic RNA. Higher order multimerization occurs at the plasma membrane, with monomeric and dimeric Gag (from the cytosolic pool) added to the growing lattice edges. Gag domains are shown in the same color scheme as in Figure 1 and Figure 2. Pink polygons depict different CA-CA interfaces as described in Figure 2.