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. 2022 Mar 8;23(6):2919. doi: 10.3390/ijms23062919

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Gene expression change induced by BI-D1870, ipatasertib, or their combination in HMCLs: (A) Expression changes in all investigated genes relative to vehicle cells in NCI-H929 (X-axis) and OPM-2 cells (Y-axis). (B) Venn diagrams for numbers of commonly significantly upregulated (left) and downregulated (right) genes in NCI-H929 and OPM-2 cells. (C) Clustering of significantly modulated genes after treatment in NCI-H929 and OPM-2 cells.

Gene expression change induced by BI-D1870, ipatasertib, or their combination in HMCLs: (A) Expression changes in all investigated genes relative to vehicle cells in NCI-H929 (X-axis) and OPM-2 cells (Y-axis). (B) Venn diagrams for numbers of commonly significantly upregulated (left) and downregulated (right) genes in NCI-H929 and OPM-2 cells. (C) Clustering of significantly modulated genes after treatment in NCI-H929 and OPM-2 cells.