Table 2.
Cancer Type | Combined Smoking and Alcohol Consumption | Smoking | Alcohol Consumption | |||
---|---|---|---|---|---|---|
Incidence | Mortality | Incidence | Mortality | Incidence | Mortality | |
HR (95% CI) | HR (95% CI) | HR (95% CI) | HR (95% CI) | HR (95% CI) | HR (95% CI) | |
Esophageal | 4.4 (2.7–7.3) * | 6.1 (2.8–13.6) * | 1.7 (1.2–2.5) * | 2.3 (1.2–4.2) * | 2.6 (1.8–3.8) * | 2.7 (1.5–4.9) * |
Stomach | 1.3 (1.1–1.5) | 1.3 (0.8–1.9) | 1.2 (1.1–1.4) | 1.4 (1.1–1.9) | 1.1 (0.9–1.0) | 0.9 (0.6–1.2) |
Liver | 1.6 (1.3-2.0) * | 2.2 (1.5–3.2) * | 1.2 (1.0–1.4) * | 1.4 (1.1–1.9) * | 1.3 (1.1–1.6) * | 1.5 (1.1–2.1) * |
Laryngeal | 3.4 (1.9–6.3) | 23.4 (1.7–313.4) | 2.2 (1.4–3.4) | 9.5 (1.1–84.9) | 1.6 (1.0–2.5) | 2.5 (0.5–12.5) |
Tracheal, bronchial, and lung | 2.3 (1.9–2.7) * | 3.3 (2.5–4.4) | 1.9 (1.7–2.2) * | 2.8 (2.3–3.4) | 1.2 (1.0–1.4) * | 1.2 (1.0–1.5) |
Colon and rectal | 1.3 (1.1–1.6) | 1.7 (1.0–2.8) | 1.1 (0.9–1.2) | 1.3 (0.9–1.9) | 1.2 (1.1–1.4) | 1.3 (0.9–1.9) |
Mouth | 1.4 (0.9–2.2) | 0.7 (0.1–3.9) | 1.1 (0.8–1.5) | 0.8 (0.3–2.8) | 1.3 (1.0–1.9) | 0.9 (0.2–3.2) |
Nasopharyngeal | 1.6 (0.5–4.7) | 2.2 (0.2–25.0) | 1.0 (0.4–2.3) | 1.3 (0.2–8.0) | 1.6 (0.7–3.6) | 1.7 (0.3–10.5) |
Other parts of the pharynx and oropharynx | 1.3 (0.6–2.8) | 4.8 (0.6–36.8) | 0.9 (0.5–1.5) | 1.2 (0.3–5.7) | 1.5 (0.9–2.7) | 3.9 (0.9–18.2) |
Gallbladder and biliary tract | 1.4 (0.9–2.3) | 1.2 (0.6–2.5) | 1.1 (0.8–1.5) | 1.3 (0.8–2.3) | 1.4 (1.0–1.9) | 0.9 (0.5–1.6) |
Pancreatic | 1.6 (1.1–2.5) | 1.9 (1.1–3.3) | 1.3 (1.0–1.8) | 1.4 (0.9–2.1) | 1.2 (0.9–1.7) | 1.4 (0.9–2.1) |
Bladder | 1.4 (0.9–2.0) | 1.8 (0.5–6.3) | 1.3 (1.0–1.7) | 1.6 (0.6–3.9) | 1.0 (0.8–1.4) | 1.2 (0.4–3.1) |
Cause-specific Cox proportional hazard modeling was used. HR, hazard ratios; CI, confidence interval. * denotes statistically significant comparisons of ‘combined smoking and alcohol consumption’, ‘smoking’, and ‘alcohol consumption’.