Table 3.

Correlation (Spearman’s Rho) between change in self-reported joint function/PA and change in molecular biomarkers.

	CRP rs	P	ARGS-aggrecan	P	COMP rs	P	C2C rs	P
KOOS/HOOS (n = 83)
Pain	0.016	.886	0.096	.389	−0.037	.744	−0.095	.391
Symptoms	−0.050	.654	0.026	.812	0.111	.318	0.141	.201
ADL	0.104	.347	0.051	.648	0.071	.521	0.112	.310
Sport/Rec	0.057	.618	−0.003	.978	−0.006	.955	−0.105	.356
QoL	0.206	.060	0.171	.120	0.032	.777	−0.100	.366
IPAQ-SF (n = 65)
MET-minutes/week	0.107	.390	−0.083	.508	−0.256	.040	−0.089	.475

Abbreviations: ADL, activities of daily living; ARGS, neoepitope of aggrecan; C2C, collagen type II cleavage; COMP, cartilage oligomeric matrix protein; CRP, C-reactive protein; HOOS, Hip disability and Osteoarthritis Outcome Score; IPAQ-SF, International Physical Activity Questionnaire–Short Form; KOOS, Knee injury and Osteoarthritis Outcome Score; MET, metabolic equivalent of tasks; PA, physical activity; QoL, knee/hip-related quality of life.