Table 1:
Frequency of expression of putative Six1 target genes in various tissues
| pax2 | OV | NT | Retina | |||
|---|---|---|---|---|---|---|
| six1+/− | 100% (5) | 100% (5) | 100% (5) | |||
| six−/− | 100% (5) | 100% (5) | 100% (5) | |||
| eya2 | OV | Olf | VIIg | IX/Xg | Hyp | Nephric |
| six1+/− | 100% (10) | 100% (10) | 100% (10) | 40% (10) | 100% (10) | 100% (10) |
| six−/− | 100% (4) but smaller, malformed | 50% (4) but reduced |
100% (4) but truncated | 0% (4) | 75% (4) but reduced | 75% (4) but reduced |
| tbx1 | OV | BA | ||||
| six1+/− | 100% (6) | 100% (6) | ||||
| six−/− | 82% (11) | 64% (11); not distinct | ||||
| dlx5 | OV | BA | Olf | |||
| six1+/− | 100% (15) | 100% (15) | 100% (15) | |||
| six−/− | 0% (8) | 0% (8) | 0% (8) | |||
| irx1 | OV | NT | ||||
| six1+/− | 100% (5) | 100% (5) | ||||
| six−/− | 0% (5) | 80% (5) | ||||
| sobp | OV | Olf | NT | VIIg | ||
| six1+/− | 100% (15) | 100% (15) | 100% (15) | 100% (15) | ||
| six−/− | 0% (5) | 0% (5) | 100% (5) but reduced | 0% (5) | ||
| rnf150 | OV | BA | NT | Retina | ||
| six1+/− | 100% (15) | 100% (15) | 100% (15) | 100% (15) | ||
| six−/− | 0% (4) | 100% (4) but reduced | 0% (4) | 0% (4) | ||
| pick1 | OV | BA | NT | Retina | ||
| six1+/− | 100% (10) | 100% (10) | 100% (10) | 100% (10) | ||
| six−/− | 0% (4) | 0% (4) | 0% (4) | 0% (4) | ||
Legend: BA, branchial arches; Hyp, hypaxial muscle precursors; Nephric, nephric mesoderm; NT, neural tube; Olf, olfactory placode; OV, otic vesicle; VIIg, facial ganglion placode; IX/Xg, glossopharyngeal/vagal ganglion placode. Numbers in brackets denote number of larvae analyzed.