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. 2022 Mar 16;12(3):480. doi: 10.3390/jpm12030480

Table 1.

Overview of published works regarding nodule detection approaches in lung CT images (2020–2021).

Authors Year Dataset Methods Performance Results (%)
Tan et al. [78] 2020 LIDC-IDRI 3D CNNs, based on FCN, DenseNet, and U-Net TPR = 97.5
Mukherjee et al. [88] 2020 LIDC-IDRI Ensemble stacking ACC = 99.5
TPR = 99.2
TNR = 98.8
FPR = 1.09
FNR = 0.85
Shi et al. [79] 2020 LUNA16 3D Res-I and U-Net network TPR = 96.4
FROC = 83.7
Khehrah et al. [86] 2020 LIDC-IDRI SVM ACC = 92
TPR = 93.7
TNR = 91.2
PPV = 83.3
MCC = 83.8
Kuo et al. [87] 2020 LIDC-IDRI Private (320 patients) SVM TPR = 92.1
Zheng et al. [80] 2020 LIDC-IDRI 3D multiscale dense CNNs TPR = 94.2 (1.0 FP/scan),
96.0 (2.0 FPs/image)
Paing et al. [89] 2020 LIDC-IDRI Optimized random forest ACC = 93.1
TPR = 94.9
TNR = 91.4
Liu et al. [100] 2020 LIDC-IDRI CNN algorithm: You Only Look Once v3 TPR = 87.3
Harsono et al. [97] 2020 LIDC-IDRI Private (546 patients) I3DR-Net mAP = 49.6 (LIDC),
22.9 (private)
AUC = 81.8 (LIDC),
70.4 (private)
Xu et al. [81] 2020 LUNA16 3D CNN networks: V-Net and multi-level contextual 3D CNNs TPR = 93.1 (1.64 FP/scan)
CPM = 75.7
Drokin and Ericheva [96] 2020 LIDC-IDRI Algorithm for sampling points from a point cloud FROC = 85.9
El-Regaily et al. [90] 2020 LIDC-IDRI Multi-view CNN ACC = 91.0
TPR = 96.0
TNR = 87.3
F-score = 78.7
Ye et al. [82] 2020 LUNA16 Three modified V-Nets with multilevel receptive fields ACC = 66.7
TPR = 81.1
PPV = 78.1
F-score = 78.7
Baker and Ghadi [93] 2020 LIDC-IDRI SVM NRR = 94.5
FPR = 7 cluster/image
Halder et al. [94] 2020 LIDC-IDRI SVM ACC = 88.2
TPR = 86.9
TNR = 86.9
Jain et al. [83] 2020 LUNA16 SumNet ACC = 94.1
TNR = 94.0
DSC = 93.0
Mahersia et al. [95] 2020 LIDC-IDRI SVM, Bayesian back-propagation neuronal classifier and neuro-fuzzy classifier NRR = 97.9
(neuronal classifier),
97.3 (SVM),
94.2 (neuro-fuzzy classifier)
Mittapalli and Thanikaiselvan [91] 2021 LUNA16 Multiscale CNN with Compound Fusions CPM = 94.8
Vipparla et al. [92] 2021 LUNA16 3D Attention-based CNN architectures: MP-ACNN1, MP-ACNN2 and MP-ACNN3 CPM = 93.1
Luo et al. [84] 2021 LUNA16 SCPM-Net TPR = 92.2 (1 FPs/image),
93.9 (2 FPs/image),
96.4 (8FPs/image)
Bhaskar and Ganashree [85] 2021 DSB-2017 Gaussian mixture convolutional auto encoder + 3D deep CNN ACC = 74.0

ACC: accuracy; AUC: area under the ROC curve; CPM: competition performance metric; DSC: Sørensen–Dice coefficient; FDR: false discovery rate; FNR: false negative rate; FP: false positive; FPR: false positive rate; FROC: free-response receiver operating characteristic; mAP: mean average precision; MCC: Matthews correlation coefficient; NPV: negative predictive value; NRR: nodule recognition rate; PPV: positive predictive value; TNR: true negative rate; TPR: true positive rate.