Table 2.
Minimum inhibitory and fungicidal concentration values (µg/mL) of the 17 nitrofuran derivatives against H. capsulatum and P. brasiliensis.
| H. capsulatum | P. brasiliensis | |||
|---|---|---|---|---|
| Compounds | MIC90 | MFC | MIC90 | MFC |
| 1 | >250 | >250 | 3.90 | 62.50 |
| 2 | 250.00 | >250 | 31.25 | 125.00 |
| 3 | 3.90 | 3.90 | 0.48 | 0.98 |
| 4 | 3.90 | 3.90 | 3.90 | 7.81 |
| 5 | 1.95 | 1.95 | 15.62 | 31.25 |
| 6 | >250 | >250 | 31.25 | 31.25 |
| 7 | 0.98 | 0.98 | 1.95 | 1.95 |
| 8 | 15.62 | 15.62 | 0.98 | 1.95 |
| 9 | 3.90 | 3.90 | 0.48 | 1.95 |
| 10 | 7.81 | 15.62 | 0.98 | 0.98 |
| 11 | 0.48 | 0.48 | 0.98 | 0.98 |
| 12 | 7.81 | 15.62 | 3.90 | 3.90 |
| 13 | 125.00 | 125.00 | 0.98 | 0.98 |
| 14 | 7.81 | 7.81 | 1.95 | 1.95 |
| 15 | >250 | >250 | 3.90 | 7.81 |
| 16 | 62.50 | 62.50 | 1.95 | 1.95 |
| 17 | >250 | >250 | 1.95 | 3.90 |
| AmB | 0.03 | - | 0.13 | - |
MIC90—minimum inhibitory concentration capable of inhibiting at least 90% growth; MFC—minimal fungicidal concentration; AmB: Amphotericin B.