Skip to main content
. 2022 Mar 17;23(6):3266. doi: 10.3390/ijms23063266

Figure 2.

Figure 2

Lactate secretion is greater in obese OA synovial fibroblasts and is induced during the inflammatory response. The effect of TNFα (10 ng/mL) stimulation of synovial fibroblasts from normal-weight (NW) or obese OA patients (n = 3) on (A) the expression of IL-6 and (B) secretion of lactate after 4 h and 24 h stimulation. Data expressed as mean ± SEM. ** = p < 0.01, *** = p < 0.001, significantly different from time 0. ‡ = p < 0.01, significantly different between synovial fibroblasts from patients with different BMI.