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. 2022 Mar 15;23(6):3167. doi: 10.3390/ijms23063167

Figure 1.

Figure 1

Simplified schematic representation of the events considered in the multiple-hit theory leading to NAFLD development. F/B: Firmicutes/Bacteroidetes ratio; FA: fatty acid; FFA: free fatty acid; HSL: hormone-sensitive lipase; IR: insulin resistance; ROS: reactive oxygen species; TG: triglyceride; VLDL: very-low-density lipoprotein; WAT: white adipose tissue. ↑: increase; ↓: decrease.