Figure 2.

Schematic representation of single-strain probiotics-mediated effects in hepatic lipid accumulation. ACC: acetyl-CoA carboxylase; AMPK: AMP protein kinase; Ac Coa: acetyl CoA; CAT: catalase; ChREBP: carbohydrate-responsive element-binding protein; CPT1a: carnitine palmitoyltransferase 1a; FA: fatty acid; FAS: fatty acid synthase; Iκβα: NF-kappa-β inhibitor α; Mal CoA: malonyl CoA; NF-κB: nuclear factor kappa B; PGC1α: peroxisome proliferator-activated receptor gamma coactivator 1-α; PPAR-α: peroxisome proliferator-activated receptor α; PPAR-γ: peroxisome proliferator-activated receptor γ; ROS: reactive oxygen species; SCFA: short-chain fatty acids; SOD: superoxide dismutase; SREBP-1: Sterol regulatory element-binding protein 1; TG: triglyceride. ↑: up-regulation; ↓: down-regulation.