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. 2022 Mar 3;10(3):394. doi: 10.3390/vaccines10030394

Table 3.

For each IGHV subgroup or clan, number of IGHV genes per functionality and, between parentheses, number of alleles.

IGHV Subgroup/Clan Functionality Total
IGHV1 11 F (13), 14 P (18) 25 (31)
IGHV2 5 F (6), 1 O (1), 1 P (1) 7 (8)
IGHV3 39 F (62), 1 O (2), 34 P (52), 2 FO (4), 2 FP (4) 78 (124)
IGHV4 19 F (25), 3 P (4), 3 FP (6) 25 (35)
IGHV5 2 F (4), 1 P (2) 3 (6)
IGHV6 1 F (1) 1 (1)
IGHV7 2 F (3), 12 P (14) 14 (17)
IGHV8 2 P (4) 2 (4)
IGHV(I) 6 P (9) 6 (9)
IGHV(II) 35 P (53) 35 (53)
IGHV(III) 32 P (48) 32 (48)
Total per functionality 79 F (114) + 2 O (3) + 140 P (205) + 2 FO (4) + 5 FP (10)
Total number of genes (and alleles) 228 (336)

F: functional; O: ORF; P: pseudogene; FO: functional or ORF; FP: functional or pseudogene; the number of alleles is indicated in the parentheses. Data available in IMGT Repertoire (IG and TR) http://www.imgt.org/IMGTrepertoire/, accessed on 11 November 2021 > Locus and genes > Gene tables > IGHV > Nonhuman Primates > Rhesus monkey (Macaca mulatta).