Table 1.
Clinical, radiological and laboratorial data from the three groups of patients according to their Cq values.
A Cq ≤ 31 (n = 32) |
B 31 > Cq < 33 (n = 9) |
C Cq ≥ 33 (n = 45) |
p Value | |
---|---|---|---|---|
Male/Female | 27/5 | 6/3 | 33/12 | 0.4 |
Age (years) | 38 ± 2.3 | 34 ± 3.7 | 41 ± 3.9 | 0.15 |
Dry cough | 60% | 11% | 25% | A × B: 0.02 A × C: 0.004 |
Productive cough | 40% | 89% | 75% | A × B: 0.02 A × C: 0.004 |
Fever | 78% | 77% | 73% | 0.88 |
PcP treatment | 90% | 11% | 28% | A × B: <0.001 A × C: <0.001 |
Tuberculosis * | 18% | 11% | 37% | 0.09 |
Presumed pulmonary CMV * | 25% | 0% | 11% | 0.052 |
Presumed CABP * | 68% | 33% | 42% | A × B: 0.054 A × C: 0.027 |
Respiratory frequency > 24 bim | 84% | 44% | 57% | A × B: 0.014 A × C: 0.013 |
Interstitial infiltrate on X-ray | 93% | 66% | 61% | A × B: 0.028 A × C: 0.001 |
Ground-grass on CT-scan | 93% | 42% | 38% | A × B: 0.001 A × C: <0.001 |
beta-D-glucan > 150 pg/mL | 93% | 11% | 11% | A × B: <0.001 A × C: <0.001 |
Days with symptoms | 43 ± 9 | 41 ± 15 | 43 ± 15 | 0.98 |
O2 saturation (%) | 88 ± 1.5 | 91 ± 2.4 | 93 ± 2.5 | A × C: 0.01 |
Lactic dehydrogenase (U/L) | 488 ± 49 | 219 ± 78 | 324 ± 81 | A × B: 0.004 A × C: 0.004 |
TCD4 cells/mm3 | 40 ± 15 | 86 ± 28 | 75 ± 28 | A × C: 0.01 A × B: 0.07 |
HIV viral load (copies/mL) | 780,289 ± 207,058 | 117,728 ± 386,509 | 304,545 ± 394,559 | A × C: 0.02 A × B: 0.07 |
BDG (pg/mL) | 441 ± 29 | 76.3 ± 46 | 62.2 ± 48 | A × B: <0.001 A × C: <0.001 |
PcP clinical index | 5 (4 − 5) | 1 (1 − 2) | 2 (1 − 3) | A × B: <0.001 A × C: <0.001 |
CABP: community acquired bacterial pneumonia; bim: breath incursions per minute, PcP: Pneumocystis pneumonia.; Continuous data expressed as mean ± SE or median and interquartile range and analyzed with ANOVA adjusted for white and post-hoc analyses with Tukey’s test.; Non-continuous data expressed as percentage and analyzed with Pearson’s chi-square; * Some patients had two or more concurrent pulmonary OIs.