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Periarterial influx of CSF into the brain tissue (small white arrow). CSF–ISF exchange supported by AQP4 channels in the vascular end feet plastered along the arterioles. From here, the fluid leaves the axons and moves towards the perivenous space in a path supported by astrocytes. Astrocytic AQP4 water channels facilitate this perivenous efflux of interstitial fluid, which drains to the dural lymphatic vessels.
