Table 1.

The short summary of three different types of resistance to immunotherapy [7].

Timing of Systemic Progression	Type of Resistance	Description
Early (<3 months)	Primary resistance	Cancer does not respond to an immunotherapy strategy
Intermediate (3 months–2 years)	Adaptive resistance	Most cancer cells are recognized by the immune system, but some cells are equipped with protective mechanisms
Late (>2 years)	Acquired resistance	Cancer initially responds to immunotherapy but after a period of time progression is observed

Based on the article: Sharma et al., 2017; modified by authors.