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Lung histopathologic examination of penicillin-resistant S. pneumoniae (strain 16089) experimental pneumonia at 24 h (A) and 48 h (B). Pneumonia with polymorphonuclear leukocytes and fibrinous exudate fill up the alveoli. Hematoxylin-eosin-safranin stain was applied to the sections. Original magnification, ×250.
