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. 2022 Mar 5;14(3):576. doi: 10.3390/pharmaceutics14030576

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Neuroprotective histopathological effect of different treatments on dentate gyrus/hippocampal subregions of AD model stained with H&E stain. (A) Normal controls, (B) model AD samples, (C) LUT suspension samples, and (D) LUT-BL samples. Microscopic examination of toluidine-blue-stained pyramidal neurons in dentate gyrus/hippocampal subregions in different groups. (E) Normal controls, (F) model AD samples, (G) LUT suspension samples, and (H) LUT-BL samples. Black arrows = intact neurons, red arrows = damaged neurons. * statistically significant difference from normal control group and ** statistically significant difference from the SAD model group.