Table 1.
% Activity relative to control (HIV-1 integrase) values obtained for the different compounds tested against HIV-1 Integrase. Compounds were assayed at a concentration of 25 μg/mL a.
| Treatment | % Activity rel. to Control | % Inhibition |
|---|---|---|
| HIV Integrase (no inhibition) | 100 | 0 |
| Pellitorine (1) | 81.0 ± 9.1 * | 19.0 |
| Oleuropein (2) | 95.3 ± 4.2 | 4.7 |
| Magnoflorine (3) | 88.0 ± 7.5 | 12.0 |
| Crotepoxide (4) | 91.0 ± 5.0 | 9.0 |
| Ent-kaurane-16β,17-diol (5) | 86.6 ± 2.1 | 13.4 |
| Crotocorylifuran (6) | 90.9 ± 5.0 | 9.1 |
| Lupeol (7) | 81.5 ± 1.2 * | 18.5 |
| Betulin (8) | 83.2 ± 13.6 | 16.8 |
| Ellagic acid (9) | 78.9 ± 5.7 * | 21.1 |
| Urolithin a (10) | 88.7 ± 5.4 | 11.3 |
| Urolithin b (11) | 90.1 ± 3.8 | 9.9 |
a Results presented as mean ± standard deviation (n = 3). The data were analyzed with the one-way ANOVA, using Dunnett’s test with a significance level set at 0.05. * p < 0.05.