Table 2.
The 10 most up- and downregulated genes in S. mutans upon sublethal CHX treatment. The full list of DE genes can be found in the Supplemental Table S1.
| Gene ID | Gene Name | Product | Log2 FC | p adj |
|---|---|---|---|---|
| D820_RS03005 | NA | PTS fructose transporter subunit IIB |
−3.2 | 1.60 × 10−6 |
| D820_RS01705 | NA | tRNA-Thr | −3.1 | 2.46 × 10−4 |
| D820_RS03010 | NA | PTS mannitol/fructose, IIC component |
−3.0 | 2.26 × 10−5 |
| D820_RS03000 | NA | PTS mannitol transporter subunit IIB |
−3.0 | 6.57 × 10−6 |
| D820_RS02990 | lacC | Tagatose-6-phosphate kinase | −3.0 | 2.40 × 10−5 |
| D820_RS02995 | lacD | Tagatose-bisphosphate aldolase | −2.9 | 6.31 × 10−6 |
| D820_RS08540 | NA | tRNA-Ser | −2.8 | 6.90 × 10−3 |
| D820_RS02980 | lacA | Galactose-6-phosphate isomerase | −2.7 | 1.24 × 10−4 |
| D820_RS02985 | lacB | Galactose-6-phosphate isomerase | −2.7 | 1.43 × 10−4 |
| D820_RS03015 | NA | Lactose-specific phosphotransferase enzyme IIA component |
−2.6 | 2.85 × 10−8 |
| D820_RS02805 | glgA | Glycogen synthase | 3.9 | 0.00 |
| D820_RS04685 | NA | ABC transporter (ATP-binding protein) |
4.0 | 0.00 |
| D820_RS06900 | NA | Hypothetical protein | 4.0 | 0.00 |
| D820_RS01630 | NA | 16S ribosomal RNA | 4.1 | 2.44 × 10−7 |
| D820_RS02745 | NA | ABC transporter (ATP-binding protein) |
4.1 | 0.00 |
| D820_RS02750 | NA | ABC transporter permease | 4.2 | 0.00 |
| D820_RS06905 | lrgB | Antiholin | 4.4 | 0.00 |
| D820_RS07700 | pflB | Formate C-acetyltransferase | 4.5 | 0.00 |
| D820_RS0109785 | NA | 23S ribosomal RNA | 5.0 | 1.79 × 10−6 |
| D820_RS0109610 | NA | 23S ribosomal RNA | 6.5 | 5.73 × 10−6 |
FC: fold change; padj: adjusted p-value; NA: not applicable.