Figure 1.

Exosomes freshly extracted from plasma of healthy subjects (20) and NAFLD-affected patients (95, 56 males and 39 females) with moderate (38) or severe (57) hepatic steatosis at recruitment time (T0) and after treatment (T2): representative TEM micrographs obtained with staining, for two increasing staining times, namely, 30 (a1–e1) and 60 s (A–E) (scale bar 100 nm); intensity-average hydrodynamic diameter and corresponding polydispersity index (PDI) determined by DLS and ζ-potential value. Mean ± SD are reported, n = 3 (F).