Skip to main content
. 2022 Feb 24;13(3):402. doi: 10.3390/genes13030402

Figure 1.

Figure 1

Brk promotes breast tumour xenograft growth (A) MDA-MB-157 cells were stably transfected with either the pRc/CMV vector (Vector), or a vector encoding wild-type (WT Brk) or kinase-inactive Brk (KM Brk), and the expression was confirmed by Western blotting with β-Actin expression as a loading control. (B) Cells were injected into the mammary fat pad of female CrTac:NCr-Fox-1(nu) athymic mice and tumour volume was calculated from the measurement of two perpendicular diameters over 118 days. Mean tumour volume (n = 10) +/− SEM is plotted. * indicates p < 0.05 (student’s t-test, WT-Brk compared to the vector control).