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. 2022 Feb 24;12(3):200. doi: 10.3390/metabo12030200

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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(A) Venn diagram demonstrating differentially expressed urine metabolites in UC vs. controls among male and female dogs. Differentially expressed metabolites in each group are outlined in the inset accompanying each group. (B) KEGG Pathway Analysis in canine UC as compared to the control group in female dogs only. The color intensity indicates the p-value (indicated in inset), whereas the size of each circle indicates the number of metabolites included in the pathway. (C) KEGG Pathway Analysis in canine UC as compared to the control group in male dogs only. The color intensity indicates the p-value (indicated in inset), whereas the size of each circle indicates the number of metabolites included in the pathway.