Figure 6.

Breed specific differences between UC vs. control. (A) Venn diagram demonstrating differentially expressed metabolites in terrier breeds vs. all other breeds among dogs with UC only and comparing it with differentially expressed metabolites in terriers and all other breeds among control dogs. Differentially expressed metabolites in each group are outlined in the inset accompanying each group. (B) Differential expression between UC vs. control of the six metabolites in terrier breeds only. Note that, of the six metabolites deemed highly discriminatory in Figure 2 and Figure 3 (highlighted in bold), only sarcosine was differentially expressed in terrier breeds. (C) Differential expression between UC and controls of the six metabolites in retriever breeds only. Note that, of the six metabolites deemed highly discriminatory in Figure 2 and Figure 3, five were differentially expressed in retriever breeds. Glycerol-3-galactoside was not differentially expressed in either terrier breeds or in retriever breed groupings.