Table 1.
Subject characteristics by group. All comparisons shown are between Urinary Carcinoma (UC) (n = 27) and controls (urolithiasis n = 8, Urinary Tract Infection (UTI) + urolithiasis, n = 8). Age is significantly different between groups (p < 0.001), with an older mean age in the UC group compared to the other two groups. The distribution of sexes also differs significantly between groups (p = 0.00921), with only male dogs in this study having urolithiasis.
| UC (n = 27) | Urolithiasis Only (n = 8) | UTI and Urolithiasis (n = 8) | All Subjects (n = 43) | p-Value † | |
|---|---|---|---|---|---|
| Age | <0.001 | ||||
| Mean (SD) | 10.9 (1.9) | 7.2 (3.9) | 6.2 (4.6) | 9.3 (3.5) | |
| Median (Range) | 11 (6–14) | 6.5 (1–13) | 7 (0.3–12) | 10 (0.3–14) | |
| Gender | 0.00921 | ||||
| Female | 15 (55.6%) | 0 | 5 (62.5%) | 20 (46.5%) | |
| Male | 12 (44.4%) | 8 (100%) | 3 (37.5%) | 23 (53.5%) | |
| Breed | |||||
| Terrier | 5 (18.5%) | 4 (50%) | 3 (37.5%) | 12 (27.9%) | 0.20218 |
| Shepherd | 5 (18.5%) | 0 | 0 | 5 (11.6%) | 0.34365 |
| Retriever | 5 (18.5%) | 0 | 1 (12.5%) | 6 (14%) | 0.60082 |
| Others | 12 (44.4%) | 4 (50%) | 4 (50%) | 20 (46.5%) | |
| Conditions | |||||
| Castrated/Spayed | 25 (92.6%) | 6 (75%) | 6 (75%) | 37 (86%) | 0.17918 |
| Urethral obstruction | 5 (18.5%) | 1 (12.5%) | 1 (12.5%) | 7 (16.3%) | 1.00000 |
| Presence of metastasis |
3 (11.1%) | 0 | 0 | 3 (7%) | |
| Treatments | |||||
| Antibiotics | 7 (25.9%) | 0 | 1 (12.5%) | 8 (18.6%) | 0.30230 |
| NSAIDS | 12 (44.4%) | 3 (37.5%) | 0 | 15 (34.9%) | 0.07110 |
| Chemotherapy | 4 (14.8%) | 0 | 0 | 4 (9.3%) |
†p-value for age is from an ANOVA F-test and p-values for categorical variables are from Fisher’s Exact Tests.