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. 2022 Mar 21;12(3):267. doi: 10.3390/metabo12030267

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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ECM detachment represses NKG2DLs–MICA/B expression. (a) Fold changes in mRNA expression of DNMTs in attached (AT) and 6 days ECM-detached (6D_DT) HeLa cell lines. (b) Fold changes in mRNA expression of DNMTs in attached (AT) and 6 days ECM-detached (6D_DT) MCF-7 cell lines. (c) Fold changes in mRNA expression of MICA/B in attached (AT) and 6 days ECM-detached (6D_DT) conditions in HeLa cell lines. (d) Fold changes in mRNA expression of MICA/B in attached (AT) and 6 days ECM-detached (6D_DT) conditions in MCF-7 cell lines. (e,f). MICA/B surface expression is repressed in the 6 days ECM-detached (6D_DT) condition compared to the attached (AT) condition in HeLa and MCF-7 cell lines. The data are presented as mean ± SEM; ns, not significant.