Figure 7.
Simplified schematic representation of the effects of compounds targeting the bd oxidase on the level of the isolated enzyme, membrane vesicles or whole cells. Shown are the structures of aurachin D, 3-[[2-(4-chlorophenyl)ethylamino]methyl]-1-ethyl-indole-2-carboxylic acid (MQL-H2), N-(4-(4-(trifluoromethyl)phenoxy)phenyl)quinazolin-4-amine (ND-011992), and N-(4-(tert-butyl)phenethyl)thieno [3,2-d]pyrimidin-4-amine (Compound 19). See the main text for details. Data collected from: [10,13,14,116,117,118,119,120,121,122,123,124].