| PCSK1 (PC1/3) |
Hypothalamus, pituitary, pancreas, thyroid gland, adrenal glands |
Regulation of appetite; activation of insulin, glucagone, orexin, ghrelin |
| PCSK2 (PC2) |
Central nervous system (CNS), pituitary, pancreas |
Regulation of carbohydrate metabolism |
| PCSK3 (furin) |
Ubiquitous |
Regulation of embryogenesis, activation of growth factors and bacterial toxins (e.g., Clostridioides spp.), carcinogenesis |
| PCSK4 (PC4) |
Germinal |
Regulation of reproduction processes |
| PCSK5 (PC5/6) |
Ubiquitous |
Regulation of embryogenesis (e.g., CNS) |
| PCSK6 (PACE4) |
| PCSK7 (PC7) |
Colon, spleen, liver |
Regulation of lipid metabolism, atherogenesis |
| SKI-1 (S1P) |
Ubiquitous |
| PCSK9 |
Liver, small intestine |
