Skip to main content
. 2022 Mar 10;23(6):2996. doi: 10.3390/ijms23062996

Figure 3.

Figure 3

Hdac expression across different cells in the sciatic nerve at P1 (early developmental stage) and P60 (mouse adulthood). Data based on 10× genomics single cell RNA sequencing data from Gerber et al. (2021). Graphs generated based on RNA-seq data from Gerber et al., 2021 (GEO database accession number GSE137870). [56]. Three independent samples were included for each time point, processed as three independent 10× Genomics runs. Expression is detailed in proliferating (prol. SC), immature (iSC), and pro-myelinating (pmSC) Schwann cells; immune cells (IC), endothelial cells (EC), pericytes, and vascular smooth muscle cells (per/VMSC), pericytes/endothelial cells (Per/EC*), endothelial cells 1 and 2 (EC1&2), proliferating fibroblast-like cells (prol. Fb), fibroblast-related cells (FbRel*), endoneurial cells (EnC, also known as endoneurial fibroblasts or fibroblast-like cells), perineurial cells (PnC), and epineurial cells (EpC). Dot colour represents average expression level in cells expressing the Hdac of interest. Dot size represents percentage of cells expressing the Hdac of interest. (* indicates tentative label suggested by Gerber et al., 2021). Futher single cell RNA-seq gene expression can be checked in the Sciatic Nerves Atlas: https://snat.ethz.ch/index.html (Accessed on 26 February 2022).