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. 2022 Feb 26;2022(2):hoac009. doi: 10.1093/hropen/hoac009
When surgery is indicated in women with an endometrioma, clinicians should perform ovarian cystectomy, instead of drainage and electrocoagulation, for the secondary prevention of endometriosis-associated dysmenorrhoea, dyspareunia and non-menstrual pelvic pain. However, the risk of reduced ovarian reserve should be taken into account.
  • Strong recommendation

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Clinicians should consider prescribing the postoperative use of a LNG-IUS system (52 mg) or a combined hormonal contraceptive for at least 18–24 months for the secondary prevention of endometriosis-associated dysmenorrhoea (Seracchioli et al., 2009; Lee et al., 2018; Song et al., 2018; Chen et al., 2020; Zakhari et al., 2021).
  • Strong recommendation

  • ⊕⊕○○

After surgical management of ovarian endometrioma in women not immediately seeking conception, clinicians are recommended to offer long-term hormone treatment (e.g. combined hormonal contraceptives) for the secondary prevention of endometrioma and endometriosis-associated related symptom recurrence.
  • Strong recommendation

  • ⊕○○○

For the prevention of recurrence of deep endometriosis and associated symptoms, long-term administration of postoperative hormone treatment can be considered.
  • Weak recommendation

  • ⊕○○○

Clinicians can perform ART in women with deep endometriosis, as it does not seem to increase endometriosis recurrence per se (Somigliana et al., 2019).
  • Weak recommendation

  • ⊕⊕⊕○