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. 2022 Mar 21;14(6):1314. doi: 10.3390/nu14061314

Table 5.

Univariate and adjusted ORs and 95 CIs for having high LDL-c and low HDL-c levels per 300 mg increase in total calcium intake and calcium from different sources.

High LDL-c
(≥2.6 mmol/L)
Low HDL-c
(<1.3 mmol/L)
Univariate Adjusted * Univariate Adjusted *
OR (95%) p-Value OR (95%) p-Value OR (95%) p-Value OR (95%) p-Value
Model 1
Total Ca intake 1.01 (0.91, 1.12) 0.805 0.95 (0.84, 1.07) 0.401 0.85 (0.75, 0.96) 0.010 0.89 (0.76, 1.05) 0.164
Model 2
Dietary Ca 0.94 (0.81, 1.1) 0.454 0.89 (0.71, 1.13) 0.343 1.04 (0.88, 1.23) 0.612 0.91 (0.70, 1.18) 0.469
Ca from supplements 1.07 (0.93, 1.23) 0.358 0.98 (0.84, 1.14) 0.769 0.71 (0.58, 0.86) 0.001 0.88 (0.72, 1.08) 0.230
Model 3
Ca from dairy products 0.93 (0.78, 1.12) 0.443 0.90 (0.69, 1.15) 0.396 1.07 (0.88, 1.29) 0.490 0.93 (0.70, 1.24) 0.622
Ca from non-dairy sources 0.99 (0.69, 1.44) 0.978 0.88 (0.53, 1.44) 0.602 0.94 (0.63, 1.39) 0.739 0.79 (0.48, 1.31) 0.362
Ca from supplements 1.07 (0.93, 1.23) 0.353 0.98 (0.84, 1.14) 0.766 0.71 (0.58, 0.86) 0.001 0.88 (0.72, 1.08) 0.226
Model 4
Ca from milk 0.96 (0.70, 1.32) 0.794 0.99 (0.64, 1.53) 0.953 1.14 (0.81, 1.62) 0.447 0.88 (0.58, 1.34) 0.540
Ca from yogurts 0.91 (0.61, 1.35) 0.624 0.88 (0.57, 1.36) 0.557 1.19 (0.73, 1.93) 0.492 1.55 (0.96, 2.50) 0.070
Ca from cheese 0.91 (0.69, 1.19) 0.493 0.83 (0.60, 1.16) 0.277 0.93 (0.7, 1.24) 0.614 0.68 (0.47, 0.99) 0.047
Ca from milk-based desserts 2.28 (0.3, 17.45) 0.428 4.52(0.42, 48.12) 0.211 5.29 (0.76, 36.85) 0.092 1.05 (0.06, 17.3) 0.970
Ca from non-dairy sources 0.99 (0.68, 1.44) 0.964 0.88 (0.53, 1.44) 0.608 0.93 (0.62, 1.38) 0.712 0.75 (0.45, 1.24) 0.263
Ca from supplements 1.07 (0.93, 1.23) 0.377 0.97 (0.84, 1.14) 0.747 0.70 (0.57, 0.85) <0.001 0.87 (0.71, 1.07) 0.199
Model 5
Ca from fermented dairy 0.91 (0.73, 1.14) 0.414 0.84 (0.65, 1.10) 0.214 1.02 (0.79, 1.3) 0.901 0.93 (0.64, 1.36) 0.704
Ca from non-fermented dairy 0.98 (0.71, 1.34) 0.893 1.01 (0.65, 1.57) 0.971 1.19 (0.85, 1.67) 0.323 0.93 (0.63, 1.39) 0.736
Ca from non-dairy sources 1.00 (0.69, 1.45) 0.999 0.88 (0.53, 1.45) 0.612 0.95 (0.64, 1.4) 0.783 0.79 (0.48, 1.31) 0.362
Ca from supplements 1.07 (0.93, 1.23) 0.353 0.98 (0.84, 1.14) 0.778 0.71 (0.58, 0.86) <0.001 0.88 (0.72, 1.08) 0.225
Model 6
Ca from high-fat dairy 0.88 (0.67, 1.16) 0.365 0.78 (0.56, 1.07) 0.126 0.91 (0.68, 1.22) 0.540 0.65 (0.45, 0.95) 0.025
Ca from low-fat dairy 0.97 (0.77, 1.23) 0.833 0.99 (0.72, 1.35) 0.936 1.20 (0.93, 1.55) 0.168 1.14 (0.83, 1.57) 0.416
Ca from non-dairy sources 1.00 (0.69, 1.45) 0.985 0.86 (0.52, 1.41) 0.550 0.94 (0.63, 1.38) 0.739 0.75 (0.45, 1.25) 0.273
Ca from supplements 1.07 (0.93, 1.23) 0.365 0.98 (0.84, 1.14) 0.776 0.70 (0.58, 0.85) <0.001 0.87 (0.71, 1.07) 0.191

* Adjusted for age, sex, weight, height, smoking status, alcohol intake, dietary energy intake, physical activity energy expenditure and use of medication (statins or other lipid-lowering drugs, antihypertensive drugs, antidiabetic drugs). Results are expressed per 300 mg increase in Ca intake (quantity provided by one serving of dairy products). Significant p-values (< 0.05) are indicated in bold. All models consider the total amount of Ca consumed. Model 1: Total Ca intake, Model 2: Ca from diet and supplements, Model 3: Ca from dairy and non-dairy sources, Model 4: Ca from dairy sources by subtype, Model 5: Ca from dairy sources by fermentation status, Model 6: Ca from dairy sources by fat content.