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. 2022 Mar 12;11(6):1567. doi: 10.3390/jcm11061567

Table 4.

Short summary of the interaction risk of the reviewed plants in RA, IBD, and osteoarthritis treatment. Details can be found in Table 3 and Section 3.2.

Interaction Potential Plants
High interaction potential, may
affect several drugs
St John’s wort, cannabis (3.2.2.), green tea (3.2.9.), echinacea (3.2.4.)
Moderate interaction potential; few drugs or lower level of evidence Flax seed, ginger, meadowsweet, psyllium, valerian, willow bark (3.2.11.)
Generally low interaction potential, but possible interaction with
cyclosporine/tacrolimus via CYP or pGP (case reports or in vitro data; Table 3)
Boswellia, chamomile, cranberry, devil’s claw (3.2.3.), garlic (3.2.6.), ginseng (3.2.7.), milk thistle, peppermint, turmeric (3.2.10.)
No interactions reported/very low-risk Artichoke, ash leaf, blackcurrant leaf, English
plantain, fennel, lemon balm, lime/linden flowers, nettle herb, rose hip, saw palmetto, soybean,
wormwood