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. Author manuscript; available in PMC: 2022 Mar 25.
Published in final edited form as: Dev Psychopathol. 2020 Dec;32(5):1696–1714. doi: 10.1017/S0954579420001455

Figure 7.

Figure 7.

Corticosterone (CORT) blocker injection (metyrapone) prevents social transmission of scarcity-adversity effects to pup engagement with a mother in a social behavior test. (a) Depiction of model of disruption of social transmission via CORT blockade (metyrapone). (b) Depiction of experimental procedure. (c) Pup engagement with mother in a social behavior test as a function of early-life rearing condition (control vs. scarcity-adversity) and pharmacological manipulation (saline vs. metyrapone injection). Data are displayed as mean (± SEM) percent time the pup spent socially engaged with the mother, as calculated from total time pups spent crawling to the mother, probing the mother, sleeping/laying on the mother, and nipple attached to the mother (** indicates p < .01; n = 8/group).