Table 1.

The values of the coefficient of determination (R²), flux (Jss), and permeation coefficient (K_p) with standard deviation (SD) for the individual drug (IBU) release kinetic models of selected polysaccharide hydrogels.

Hydrogels	R2 (Zero-Order)	R2 (First-Order)	R2 (Higuchi)	R2 (Korsmeyer-Peppas)	R2 (Hixson-Crowell)	Jss (μg.cm2.h−1)	Kp × 103 (cm.h−1) ± (SD)
4% MC	0.9520	0.9817	0.9878	0.9430	0.9331	48.103	1.896 ± 0.043
6% MC	0.9817	0.9901	0.9880	0.9719	0.9898	53.035	2.050 ± 0.070
2% HPMC	0.9636	0.9912	0.9661	0.9907	0.9841	53.693	2.118 ± 0.054
4% HEC	0.9507	0.9807	0.9907	0.9794	0.9730	55.710	2.213 ± 0.024
6% HEC	0.9687	0.9922	0.9977	0.9871	0.9863	48.899	1.8889 ± 0.026
6% NaCMC	0.9704	0.9768	0.9866	0.9863	0.9792	50.689	1.983 ± 0.023
8% CMC	0.9501	0.9853	0.9939	0.9802	0.9758	51.038	2.029 ± 0.008
10% CMC	0.9767	0.9937	0.9972	0.9832	0.9901	52.889	2.086 ± 0.012
2% TRG	0.9108	0.9694	0.9754	0.9455	0.9534	61.102	2.416 ± 0.014
4% TRG	0.9744	0.9967	0.9980	0.9901	0.9930	61.014	2.420 ± 0.016
6% TRG	0.9322	0.9703	0.9830	0.9769	0.9598	57.205	2.267 ± 0.014
8% CRG	0.9621	0.9912	0.9972	0.9899	0.9839	52.537	2.084 ± 0.011
10% CRG	0.9583	0.9847	0.9943	0.9926	0.9773	58.136	2.309 ± 0.012
4% XTG	0.9342	0.9775	0.9866	0.9815	0.9656	52.554	2.068 ± 0.006
6% XTG	0.9498	0.9842	0.9913	0.9714	0.9771	56.693	2.240 ± 0.014
2% CS HMW	0.9813	0.9800	0.9507	0.9290	0.9796	30.836	1.230 ± 0.002
3% CS HMW	0.9342	0.9298	0.8668	0.8434	0.7566	18.567	0.729 ± 0.017
2% CSc	0.9956	0.9931	0.9607	0.9740	0.9941	24.677	0.936 ± 0.011
3% CSc	0.9905	0.9908	0.9683	0.9903	0.9909	7.233	0.287 ± 0.002
2% CSs	0.9994	0.9976	0.9835	0.9405	0.9781	29.831	1.207 ± 0.048
3% CSs	0.9721	0.9721	0.9660	0.9689	0.9720	18.239	0.721 ± 0.004