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. 2022 Mar 8;27(6):1763. doi: 10.3390/molecules27061763

Table 5.

Constitutive expression of CNR1, CNR2, FAAH, and MGLL mRNA in PBMCs from HCs and pwMS.

Target Gene HC MS p Value
CNR1 average delta Ct * 20.8 ± 0.2 20.3 ± 0.9 0.4635
CNR2 average delta Ct 17.1 ± 0.2 16.6 ± 0.4 0.1867
FAAH average delta Ct 19.1 ± 0.2 18.7 ± 0.4 0.2802
MGLL average delta Ct 13.4 ± 0.3 13.1 ± 0.6 0.6103

The table includes mean delta Ct values ± SEM for CNR1, CNR2, FAAH and MGLL in untreated PBMCs. CNR1: cannabinoid receptor 1; CNR2: cannabinoid receptor 2; FAAH: fatty acid amide hydrolase; HC: Healthy control; MGLL: monoacylglycerol lipase; MS: Multiple sclerosis. Values are available for 19–24 HC cases and 9–17 pwMS. Statistical analysis: Unpaired t-test. * delta Ct = Ct of target gene–Ct of housekeeping gene.