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. 2022 Feb 28;14(3):537. doi: 10.3390/pharmaceutics14030537

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effects of the P_EE_NPPCH on cell growth and the inflammatory response. (A) Photomicrographs of KERTr cells after treatment with P-KSFM for 0, 1, 3, 5, and 7 days, in which the P_EE_NPPCHs were prepared with 0.6, 6, or 60 μg/mL EGF. The group cultured with KSFM alone ([EGF] = 0 μg/mL) was employed as the control. Scale bar = 50 μm. (B) The kinetic profiles of KERTr cell growth after treatment with KSFM or various P-KSFMs within seven days. Values are presented as mean ± s.d. (n = 3). * p < 0.05 compared to the group with KSFM alone. (C) IL-8 expression levels in the KERTr cells after treatment with control media, IIM, P-IIM, or IIM + NADGA for 12 h. Values are presented as the mean ± s.d. (n = 3). * p < 0.05.